发明名称 METHOD OF DIAGNOSING AFFECTION OF PERIPHERAL NERVES IN LABORATORY ANIMALS IN REMOTE PERIOD OF EXPOSURE TO MERCURIC CHLORIDE
摘要 FIELD: medicine.SUBSTANCE: invention relates to field of medicine, in particular to experimental medicine. Stimulatory myography is performed to laboratory animals 9 weeks after exposure to toxicant is stopped. Amplitude of M-response (mV) and duration of M-response (ms) on median nerve are registered. Area of involvement of motor units is calculated. Calculation of canonic value is performed. Obtained results are compared with constant and if Cv is higher than 8.9, conclusion about absence of signs of chronic exposure to mercuric chloride is made, if Cv is lower or equals 8.9, affection of peripheral nerves in remote period of exposure to mercuric chloride is diagnosed.EFFECT: method makes it possible to eliminate killing of animals and is simpler in implementation.1 tbl, 3 ex
申请公布号 RU2497448(C1) 申请公布日期 2013.11.10
申请号 RU20120116258 申请日期 2012.04.23
申请人 FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE "VOSTOCHNO-SIBIRSKIJ NAUCHNYJ TSENTR EHKOLOGIICHELOVEKA" SIBIRSKOGO OTDELENIJA ROSSIJSKOJ AKADEMII MEDITSINSKIKH NAUK 发明人 RUSANOVA DINA VLADIMIROVNA;SOSEDOVA LARISA MIKHAJLOVNA;JAKIMOVA NATAL'JA LEONIDOVNA
分类号 A61B5/0488;G09B23/28 主分类号 A61B5/0488
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