| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: powder composition for intrapulmonary administration contains particles of ciprofloxacin betaine 3,5-hydrate and an excipient. The particles have a mass median aerodynamic diameter making from approximately 1 to approximately 5 mcm; a pulmonary half-life of betaine 3,5-hydrate makes min. 1.5 h; while a roughness of the composition falls within the range of 3 to 10.EFFECT: composition may be used to treat an endobronchial infection, such as an infection caused by Pseudomonas aeruginosa, and it is most applicable for treating mucoviscidosis.6 cl, 8 dwg, 16 tbl, 12 ex |
