FULLY HUMAN ANTIBODIES AGAINST HUMAN 4-1BB (CD137)
摘要
Fully human antibodies and antigen-binding portions thereof that bind to human 4-1BB and that allow binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating a disease in a subject comprising administering a therapeutically effective amount of the antibody to said subject.
申请公布号
HRP20130922(T1)
申请公布日期
2013.11.08
申请号
HR2013P000922T
申请日期
2013.09.30
申请人
BRISTOL-MYERS SQUIBB COMPANY
发明人
JURE-KUNKEL, MARIA;HEFTA, LAURA J.;SANTORO, MARC;GANGULY, SUBINAY;HALK, EDWARD L.