发明名称 Composicion vacunal para el control de las infestaciones por ectoparasitos que comprende un peptido de la proteina ribosomal p0 de dichos ectoparasitos; uso de la composicion para preparar medicamento efectivo para control de las infestaciones por garrapatas y/o piojos de mar y/o la transmision de sus patógenos asociados.
摘要 The present invention relates to the use of a peptide of P0 ribosomal protein in the manufacture of a vaccine composition to control of ectoparasite infestations and therefore the transmission of their associated pathogens. This peptide is located between 267 and 301 amino acids of the P0 protein, and can be obtained by recombinant means or by chemical synthesis. This peptide can be fused to a carrier protein or peptide, or an immuno-carrier and be included in an oily formulation. The formulations comprising the peptide vaccine confer protection against ticks and ectoparasites known as "sea lice" without generating autoimmunity in the host organism. Among these ticks may be mentioned species as Rhipicephalus microplus, Rhipicephalus sanguineus and Ixodes scapularis, and between sea lice are those of the Caligus and Lepeophtheirus genera.
申请公布号 CL2013000876(A1) 申请公布日期 2013.11.08
申请号 CL20130000876 申请日期 2013.03.28
申请人 CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA 发明人 RODRIGUEZ MALLON, ALINA;FERNANDEZ DIAZ, ERLINDA;ESTRADA GARCIA, MARIO, PABLO;CARPIO GONZALEZ, YAMILA
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