Ensayo de union a blanco in vitro de funcion dual no basado en celulas para la deteccion de anticuerpos blancos y anticuerpos neutralizantes contra dichos anticuerpos blancos.

摘要

An in vitro assay method is disclosed. This non-cell-based dual function target binding assay is useful for detecting both an IgG target antibody, such as a biologic drug, in a biological sample (e.g., a serum sample) and the presence of neutralizing antibodies (NAb) against the IgG target antibody.