发明名称 USE OF HIGH DOSE LAQUINIMOD FOR TREATING MULTIPLE SCLEROSIS
摘要 <p>Disclosed herein are methods of treating a human patient afflicted with multiple sclerosis or presenting a clinically isolated syndrome, methods for treating a human subject by providing neuroprotection to the human subject, and methods of treating a human patient afflicted with multiple sclerosis or presenting a clinically isolated syndrome by increasing the time to confirmed disease progression, increasing the time to confirmed relapse or reducing brain atrophy in the human patient, comprising orally administering to the human patient or subject a daily dose of about 1.2 mg laquinimod or a pharmaceutically acceptable salt thereof. The subject invention also provides a pharmaceutical oral unit dosage form of about 1.2 mg laquinimod or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier for use in treating a human patient afflicted with multiple sclerosis or presenting a clinically isolated syndrome.</p>
申请公布号 WO2013166166(A1) 申请公布日期 2013.11.07
申请号 WO2013US39090 申请日期 2013.05.01
申请人 TEVA PHARMACEUTICAL INDUSTRIES LTD.;TEVA PHARMACEUTICALS USA, INC.;BAR-ZOHAR, DAN 发明人 BAR-ZOHAR, DAN
分类号 A61K31/47 主分类号 A61K31/47
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