摘要 |
<p>The present invention provides a novel amorphous solid dispersion of desvenlafaxine succinate in combination with soluplus, process for its preparation and pharmaceutical compositions comprising it. In one aspect, the present invention provides amorphous solid dispersion of desvenlafaxine succinate in combination with soluplus. In another aspect, the present invention there is provided a process for the preparation of amorphous solid dispersion of desvenlafaxine succinate in combination with soluplus, which comprises: a) preparing a solution comprising a mixture of desvenlafaxine succinate and soluplus in a solvent; and b) removing the solvent to obtain amorphous solid dispersion of desvenlafaxine succinate in combination with soluplus. Yet in another aspect, the present invention provides pharmaceutical compositions comprising a therapeutically effective amount of amorphous solid dispersion of desvenlafaxine succinate along with soluplus, and at least one pharmaceutically acceptable excipient.</p> |
申请人 |
HETERO RESEARCH FOUNDATION;PARTHASARADHI REDDY, BANDI;RATHNAKAR REDDY, KURA;MURALIDHARA REDDY, DASARI;SUBASH CHANDER REDDY, KESIREDDY;VAMSI KRISHNA, BANDI |
发明人 |
PARTHASARADHI REDDY, BANDI;RATHNAKAR REDDY, KURA;MURALIDHARA REDDY, DASARI;SUBASH CHANDER REDDY, KESIREDDY;VAMSI KRISHNA, BANDI |