发明名称 |
.BETA.-GLUCAN IMMUNOTHERAPEUTIC METHODS |
摘要 |
<p>This disclosure describes, in one aspect, a method for identifying ß-glucan binding to immune cells of a subject. Generally, the method includes obtaining a blood sample from the subject, the blood sample comprising immune cells, adding soluble ß-glucan to at least a portion of the blood sample and incubating the mixture under conditions allowing the soluble ß-glucan to bind to the immune cells, and detecting soluble ß-glucan bound to the immune cells. In another aspect, this disclosure describes a method that generally includes identifying the subject as a low binder of ß-glucan, and co-administering to the subject a soluble ß-glucan and an antibody preparation capable of converting the subject from a low binder to a high binder.</p> |
申请公布号 |
CA2872009(A1) |
申请公布日期 |
2013.11.07 |
申请号 |
CA20132872009 |
申请日期 |
2013.03.14 |
申请人 |
BIOTHERA, INC. |
发明人 |
GROSSMAN, WILLIAM J.;ANTONYSAMY, MARY A.;WALSH, RICHARD M.;NELSON, MARIANA I.;BOSE, NANDITA;DANIELSON, MICHAEL E.;MICHEL, KYLE S. |
分类号 |
A61K31/716;C07K16/18;G01N33/53 |
主分类号 |
A61K31/716 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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