Use of A-ring aromatic acetyl minocycline and pharmaceutical preparations derived from same for treatment and prevention of inflammation, autoimmune disorders and rejection of transplants
摘要
<p>Use of A-ring aromatized acetyl minocycline compounds (I) for treating T cell-mediated diseases, is claimed. Use of A-ring aromatized acetyl minocycline compounds of formula (I) for treating T cell-mediated diseases, is claimed. R1-R5 : acetyl or H, where at least one of R1-R5 is acetyl. An independent claimS included for a pharmaceutical composition comprising A-ring aromatized acetyl minocycline compounds (I) and a pharmaceutical acceptable carrier. [Image] ACTIVITY : Antiallergic; Immunosuppressive. Test details are described but no results for the compounds of the claims are given. MECHANISM OF ACTION : None given.</p>
申请公布号
EP2659887(A1)
申请公布日期
2013.11.06
申请号
EP20120166649
申请日期
2012.05.03
申请人
OTTO-VON-GUERICKE-UNIVERSITAET MAGDEBURG
发明人
KREUTZMANN, PETER, DR.;LORENZ, PETER, DR.;REINHOLD, DIRK, PROF. DR.;GOIHL, ALEXANDER;ENTZ, DOMINIK;FRANZ, CLAUDIA;SCHRAVEN, BURKHART, PROF. DR.;FISCHER, KLAUS-DIETER, PROF. DR.