发明名称 |
HETEROAROMATIC ARYL TRIAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS |
摘要 |
<p>This invention is directed to compounds of formula I having the structure which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula I. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I.</p> |
申请公布号 |
EP2513106(B1) |
申请公布日期 |
2013.11.06 |
申请号 |
EP20100797991 |
申请日期 |
2010.12.15 |
申请人 |
H. LUNDBECK A/S |
发明人 |
PUESCHL, ASK;NIELSEN, JACOB;KEHLER, JAN;KILBURN, JOHN, PAUL;MARIGO, MAURO;LANGGAARD, MORTEN |
分类号 |
C07D471/04;A61K31/4196;A61K31/437;A61P25/18;A61P25/28 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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