发明名称 |
THE USE OF DEFERIPRONE AND METHODS TO TREAT AND/OR PREVENT FRIEDREICH ATAXIA RESULTING FROM INTRACELLULAR MISHANDLING OF IRON |
摘要 |
<p>A therapeutically effective amount of deferiprone or deferasirox or physiologically acceptable salts thereof for the prevention, stabilization, treatment, or reversal of iron-induced FRDA disease in patients resulting from mitochondrial iron-induced damage to preferentially reduce the iron stores in the mitochondria. Also for the treatment of other conditions affecting the brain where a key element in the generation of the resultant pathology is the intracellular mishandling of iron.</p> |
申请公布号 |
EP1991225(B1) |
申请公布日期 |
2013.11.06 |
申请号 |
EP20070701800 |
申请日期 |
2007.02.21 |
申请人 |
APOTEX TECHNOLOGIES INC. |
发明人 |
MUNNICH, ARNOLD;SPINO, MICHAEL;CABANTCHIK, IOAV |
分类号 |
A61K31/195;A61K31/4196;A61K31/4412 |
主分类号 |
A61K31/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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