发明名称 |
RECOMBINANT VECTOR COMPRISING CYTOCROME P450 REDUCTASE GENES, MICROORGANISM TRANSFORMED THEREOF AND METHOD FOR PRODUCING P450 ENZYME-DERIVED COMPOUNDS USING THE SAME |
摘要 |
The present invention relates to a recombinant vector comprising CPR gene which increases catalytic activity of P450 enzyme, bacteria transformed by the recombinant vector and a recombinant vector comprising P450 gene, and a method for producing a P450 catalysis compound using the same. The recombinant vector according to the present invention comprises a recombinant vector which increases the catalytic activity of P450 enzyme and has a rice-derived NADPH-cytochrome P450 reductase 2 gene consisting of base sequences of sequence number 12. The bacteria according to the present invention comprises: the recombinant vector having the rice-derived NADPH-cytochrome P450 reductase 2 gene consisting of base sequences of sequence number 12; and a recombinant vector comprising tryptamine 5-hydroxylase gene or a recombinant vector comprising cinnamate 4-hydroxylase gene. Serotonin or coumaric acid is stably produced in large amounts using the transformed bacteria. |
申请公布号 |
KR20130121420(A) |
申请公布日期 |
2013.11.06 |
申请号 |
KR20120044596 |
申请日期 |
2012.04.27 |
申请人 |
INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY |
发明人 |
BACK, KYOUNG WHAN;PARK, SANG KYU |
分类号 |
C12N15/63;C12N15/29;C12N15/53;C12N15/70 |
主分类号 |
C12N15/63 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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