发明名称 |
AAV vectors and corresponding nucleotide sequences and methods |
摘要 |
<p>The present disclosure relates to recombinant adeno-associated virus (AAV) vector serotype, wherein the capsid protein of AAV serotypes is mutated at single or multiple sites. The disclosure further relates to an improved transduction efficiency of these mutant AAV serotypes. The AAV serotypes disclosed are AAV1, AAV2, AAV3, AAV4, AAV5, AAV6, AAV7, AAV8, AAV9, AAV10. The instant disclosure relates to nucleotide sequences, recombinant vector, methods and kit thereof.</p> |
申请公布号 |
EP2660325(A2) |
申请公布日期 |
2013.11.06 |
申请号 |
EP20130166332 |
申请日期 |
2013.05.02 |
申请人 |
CHRISTIAN MEDICAL COLLEGE |
发明人 |
HAREENDRAN, SANGEETHA;GABRIEL, NISHANTH;SEN, DWAIPAYAN;GADKAR, RUPALI;GOVINDARAJAN, SUDHA;SRINIVASAN, NARAYANA SWAMY;SRIVASTAVA, ALOK;JAYANDHARAN, GIRIDHARA RAO;SELOT, RUCHITA;BALAKRISHNAN, BALAJI;KRISHNAGOPAL, AKSHAYA |
分类号 |
C12N15/864;A61K48/00 |
主分类号 |
C12N15/864 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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