| 发明名称 |
A NON-SELECTIVE CATION CHANNEL IN NEURAL CELLS AND SUR1 ANTAGONISTS FOR TREATING BRAIN SWELLING |
| 摘要 |
<p>The present invention provides compounds that block the NC Ca-ATP channel for use in (a) the prevention or treatment of neural cell swelling in the brain of a subject; (b) the alleviation of the negative effects of traumatic brain injury or cerebral ischemia stemming from neural cell swelling in a subject; (c) treating a subject having central or peripheral nervous system damage; or (d) treating a subject having bleeding in the brain.</p> |
| 申请公布号 |
EP1529058(B1) |
申请公布日期 |
2013.11.06 |
| 申请号 |
EP20030718003 |
申请日期 |
2003.03.20 |
| 申请人 |
UNIVERSITY OF MARYLAND BALTIMORE;THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS |
发明人 |
SIMARD, J., MARC;CHEN, MINGKUI |
| 分类号 |
A61K31/00;G01N33/50;A61K31/175;A61K31/426;A61K31/4439;A61K31/64;A61K45/00;A61P7/10;A61P25/00;A61P43/00;B01J19/00;B01L3/00;B29C65/48;B81B1/00;C07K14/705;C12N5/06;C12N5/08;C12Q1/02;G01N27/447;G01N33/15;G01N33/68 |
主分类号 |
A61K31/00 |
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