发明名称 Use of indole derivatives as NURR-1 activators for treating parkinson's disease
摘要 The present invention relates to a compound derived from indole, especially a therapeutically useful compound, characterized in that it is selected from compounds of formula (I) in which R1 represents a halogen or a trifluoromethyl group, R2 represents a hydrogen atom or a C1-C4 alkyl group, R3 represents an isopropyl (1-methylethyl) group or a tert-butyl (1,1-dimethylethyl) group and n=3 or 4 and pharmaceutically acceptable salts of said compounds of formula (I). Application: Treatment of neurodegenerative diseases and more particularly of Parkinson's disease.
申请公布号 US8575210(B2) 申请公布日期 2013.11.05
申请号 US200913003554 申请日期 2009.07.09
申请人 BOUBIA BENAISSA;VAN VLIET JOHANNES BERNARD;DEN HARTOG JOSEPH ANTONIUS JACOBUS;MCCREARY ANDREW;TALLANDIER MIREILLE;VAN DONGEN PETRONELLA JOHANNA MARIA;POUPARDIN-OLIVIER OLIVIA;LABORATOIRES FOURNIER SA 发明人 BOUBIA BENAISSA;VAN VLIET JOHANNES BERNARD;DEN HARTOG JOSEPH ANTONIUS JACOBUS;MCCREARY ANDREW;TALLANDIER MIREILLE;VAN DONGEN PETRONELLA JOHANNA MARIA;POUPARDIN-OLIVIER OLIVIA
分类号 A61K31/405;C07D209/04 主分类号 A61K31/405
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