发明名称 |
Use of indole derivatives as NURR-1 activators for treating parkinson's disease |
摘要 |
The present invention relates to a compound derived from indole, especially a therapeutically useful compound, characterized in that it is selected from compounds of formula (I) in which R1 represents a halogen or a trifluoromethyl group, R2 represents a hydrogen atom or a C1-C4 alkyl group, R3 represents an isopropyl (1-methylethyl) group or a tert-butyl (1,1-dimethylethyl) group and n=3 or 4 and pharmaceutically acceptable salts of said compounds of formula (I). Application: Treatment of neurodegenerative diseases and more particularly of Parkinson's disease.
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申请公布号 |
US8575210(B2) |
申请公布日期 |
2013.11.05 |
申请号 |
US200913003554 |
申请日期 |
2009.07.09 |
申请人 |
BOUBIA BENAISSA;VAN VLIET JOHANNES BERNARD;DEN HARTOG JOSEPH ANTONIUS JACOBUS;MCCREARY ANDREW;TALLANDIER MIREILLE;VAN DONGEN PETRONELLA JOHANNA MARIA;POUPARDIN-OLIVIER OLIVIA;LABORATOIRES FOURNIER SA |
发明人 |
BOUBIA BENAISSA;VAN VLIET JOHANNES BERNARD;DEN HARTOG JOSEPH ANTONIUS JACOBUS;MCCREARY ANDREW;TALLANDIER MIREILLE;VAN DONGEN PETRONELLA JOHANNA MARIA;POUPARDIN-OLIVIER OLIVIA |
分类号 |
A61K31/405;C07D209/04 |
主分类号 |
A61K31/405 |
代理机构 |
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