发明名称 Benzofurane, benzothiophene, benzothiazol derivatives as FXR modulators
摘要 The present invention relates to compounds of formula (I) wherein the substituents are as defined in the claims, including pharmaceutical compositions thereof and for their use in the treatment and/or prevention and/or amelioration of one or more symptoms of disease or disorders related to the activity of FXR. The invention is also directed to intermediates and to a method of preparation of compounds of formula (I).
申请公布号 US8575161(B2) 申请公布日期 2013.11.05
申请号 US20090988147 申请日期 2009.03.30
申请人 ROCHE DIDIER;MAUTINO GISELE;KOBER INGO;CONTARD FRANCIS;CHRISTMANN-FRANCK SERGE;SENGUPTA SAUMITRA;SISTLA RAMESH;RAO GUMMADI VENKATESHWAR;MERCK PATENT GMBH 发明人 ROCHE DIDIER;MAUTINO GISELE;KOBER INGO;CONTARD FRANCIS;CHRISTMANN-FRANCK SERGE;SENGUPTA SAUMITRA;SISTLA RAMESH;RAO GUMMADI VENKATESHWAR
分类号 A61P3/00;A61K31/343;C07D307/85;C07D405/04;C07D405/12 主分类号 A61P3/00
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