发明名称 Method for manufacturing neuraminic acid derivatives
摘要 Methods for manufacturing neuraminic acid compounds and synthetic intermediates of neuraminic acid compounds, including a method for manufacturing a compound represented by wherein R2 represents a C1-C4 alkyl, R3 represents a C1-C6 alkyl, R4 and R5 represent a hydrogen atom, a C1-C6 alkyl or a phenyl, or R4 and R5 together form a tetramethylene, a pentamethylene or an oxo, and Ac represents an acetyl, comprising reacting a compound represented by wherein R2 represents a C1-C4 alkyl, R3 represents a C1-C6 alkyl, R4 and R5 represent a hydrogen atom, a C1-C6 alkyl or a phenyl, or R4 and R5 together form a tetramethylene, a pentamethylene or an oxo, with trimethylsilyl azide in the presence of a Lewis acid.
申请公布号 US8575370(B2) 申请公布日期 2013.11.05
申请号 US201313795050 申请日期 2013.03.12
申请人 DAIICHI SANKYO CO., LTD.;DAIICHI SANKYO COMPANY, LIMITED 发明人 NAKAMURA YOSHITAKA;WAKAYAMA MASAKAZU;UMEO KAZUHIRO
分类号 C07D407/06 主分类号 C07D407/06
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