发明名称 |
PROCESSO PARA A PREPARAÇÃO DE 6-ÉSTER DE SACAROSE POR ESTERIFICAÇÃO DE CATALISADOR SUPERÁCIDO SÓLIDO |
摘要 |
One embodiment of the present invention is a process of making sucrose-6-ester from sucrose by transesterification in the presence of a solid super acid catalyst such as SO<SUB>4</SUB><SUP>2-</SUP>-TiO<SUB>2</SUB>/Al<SUB>2</SUB>O<SUB>3 </SUB>or SO<SUB>4</SUB><SUP>2-</SUP>-TiO<SUB>2</SUB>. The sucrose-6-acetate is then chlorinated to afford sucralose-6-acetate, using BTC or thionyl chloride. Sucralose-6-acetate is converted into TPSGA for the purpose of purification. TPSGA is de-esterified by sodium methoxide/methanol or sodium ethoxide/ethanol to give sucralose. |
申请公布号 |
BRPI0718058(A2) |
申请公布日期 |
2013.11.05 |
申请号 |
BR2007PI18058 |
申请日期 |
2007.10.24 |
申请人 |
MAMTEK INTERNATIONAL LIMITED |
发明人 |
DAVID LOSAN HO;ZHENGHAO WAN |
分类号 |
C07H1/00;C07H13/02 |
主分类号 |
C07H1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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