PHARMACEUTICALLY ACTIVE PHOSPHATE BINDERS, THEIR MANUFACTURE, COMPOSITIONS CONTAINING THEM AND THEIR USE

摘要

A substance for use as a medicament, comprises a solid mixed metal compound of formula (I): M^II_1-aM^III_aO_bA^n-_c.zH₂O (I) where M^II is at least one bivalent metal: M^III bis at least one trivalent metal; A^n- is at least one n-valent anion; 2+a=2b+Sigmacn; and Sigmacn<0.9a. The substance may be made by heating at a temperature of from 200° C. to 600° C. preferably from 250° C. to 500° C. of a substance comprising a compound of formula (II): M^II_1-xM^III_x(OH)₂A^n-_y.mH₂O (II) where M^II is at least one bivalent metal; M^III is at least one trivalent metal; A^n- is at least one n-valent anion; x=Sigmayn 0