发明名称 |
METHOD OF TREATMENT WITH BRAF INHIBITOR. |
摘要 |
<p>The disclosure is directed to a method of treating humans suffering from V600 mutant melanoma that incorporates the detection of the presence or absence of at least one mutation in at least one NRAS protein and/or at least one MEK1 protein, or a gene encoding said protein, and subsequently initiating treatment, modifying treatment, or discontinuing treatment with a chemotherapeutic agent selected from a BRaf inhibitor or other suitable agent based upon the presence or absence of said mutation.</p> |
申请公布号 |
MX2013005668(A) |
申请公布日期 |
2013.11.04 |
申请号 |
MX20130005668 |
申请日期 |
2011.11.18 |
申请人 |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED |
发明人 |
LIU, LI;GILMER, TONA M.;GREGER, JAMES G., JR.;BLEAM, MAUREEN;LAQUERRE, SYLVIE G. |
分类号 |
A61K31/44;C07D401/00;C07D417/00;C07D417/14;C12Q1/68;G01N33/53 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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