发明名称 NOUVEAUX COPOLYMERES A BLOC ET LEURS UTILISATIONS POUR DELIVRER UNE SUBSTANCE ACTIVE DANS UNE CELLULE.
摘要 <p>Copolymer having a block A of poly (2-methyl-2-oxazoline) and/or their derivatives and a block B of poly(tetrahydrofuran), where an average molar mass number of the copolymer is less than 6900 Dalton (Da), preferably = 6000 or 5500 Da; and the molar ratio of units A to units B is 0.4-10, preferably 0.4-6 or 0.7-5.5, is claimed. Independent claims are included for: (1) a composition comprising elements containing an active substance which is anionic molecules, preferably nucleic acids, and/or molecule used in the treatment of cancer for e.g. curcumin, and excipients, carriers, diluents or adjuvants; and (2) kit for delivering the active substance in cells or to a host, preferably a human or non human mammal, comprising the copolymer or the composition, instructions and active substance. - ACTIVITY : Cytostatic; Metabolic; Immunostimulant; CNS-Gen.; Respiratory-Gen.; Hemostatic; Anti-HIV; Antianemic; Antisickling; Muscular-Gen.; Antiparasitic; Antibacterial; Virucide; Antidiabetic. - MECHANISM OF ACTION : None given.</p>
申请公布号 FR2963350(B1) 申请公布日期 2013.11.01
申请号 FR20100056334 申请日期 2010.07.30
申请人 UNIVERSITE D'EVRY-VAL-D'ESSONNE 发明人 CHERADAME HERVE;GUEGAN PHILIPPE;RASOLONJATOVO BASOLY;SASSATELLI MATHIEU;PITARD BRUNO
分类号 C08G73/00;A61K31/12;A61K31/704;A61K31/7088;A61K47/34;A61P35/00 主分类号 C08G73/00
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