发明名称 SPHERICAL PARTICLE OF CLOPIDOGREL BISULFATE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND METHOD OF PREPARATION THEREOF
摘要 <p>The present invention relates to spherical particles of clopidogrel bisulfate and a pharmaceutical composition containing the same. The inventive spherical particles can be used for preparing a tablet having sufficient hardness through direct compression, by improving unformulable properties of clopidogrel bisulfate such as compressibility, flowability and strong surface electrostatic charges, reduce a problem in compressing tablets such as weight variation, sticking, etc., and the risk of form conversion, and improve physiochemical stability. Therefore, the spherical particles of the present invention may be used as therapeutics for arteriosclerosis, stroke, myocardial infarction and atherosclerosis.</p>
申请公布号 KR101324862(B1) 申请公布日期 2013.11.01
申请号 KR20110069039 申请日期 2011.07.12
申请人 发明人
分类号 A61K9/16;A61K9/20;A61K31/4365;C07D495/04 主分类号 A61K9/16
代理机构 代理人
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