发明名称 COMBINATION COMPRISING PYRIMIDYLAMINOBENZAMIDE COMPOUND AND Thr315Ile KINASE INHIBITOR
摘要 PROBLEM TO BE SOLVED: To provide a pharmaceutical combination for treating or preventing a proliferative disease.SOLUTION: A pharmaceutical combination comprises: (a) a specific pyrimidylaminobenzamide compound, or N-oxide or a pharmaceutically acceptable salt of the compound; and (b) a Thr315Ile kinase inhibitor selected from a specific compound group. The use of the pharmaceutical combination is provided, relating to the manufacture of pharmaceuticals for treating or preventing a proliferative disease. A proliferative disease is selected from tumors, leukemias, psoriasis, restenosis, sclerodermitis and fibrosis.
申请公布号 JP2013224304(A) 申请公布日期 2013.10.31
申请号 JP20130119191 申请日期 2013.06.05
申请人 NOVARTIS AG 发明人 MANLEY PAUL W
分类号 A61K31/506;A61K31/505;A61K45/00;A61P9/10;A61P17/00;A61P17/06;A61P35/00;A61P35/02;A61P43/00 主分类号 A61K31/506
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