| 摘要 |
A binding agent of the Formula A-a':a-S-b:b'-B:X(n), wherein A as well as B is a monovalent binder, a':a as well as b:b' is a binding pair wherein a' and a do not interfere with the binding of b to b' and vice versa, S is a spacer of at least 1 nm in length, :X denotes a functional moiety bound either covalently or via a binding pair to at least one of a', a, b, b' or S, (n) is an integer and at least 1, - represents a covalent bond, and the linker a-S-b has a length of 6 to 100 nm. Also disclosed are methods of producing such binding agent and certain uses thereof.
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