Methods for detecting contaminants in solutions containing glucose polymers

摘要

The invention relates to a method for detecting contaminants in glucose polymers, said contaminants being capable of triggering, separately or in combination, an inflammatory reaction, characterized in that it includes at least one in vitro inflammatory response test using a cell line enabling at least one inflammatory response factor to be detected, the cell line being either a macrophage or a macrophage-differentiated cell line, or a cell expressing one or more Toll-like receptors (TLRs) or NOD-like receptors such as TLR2, TLR4 or NOD2 and enabling the responses of the receptor(s) to be detected, or a combination thereof.