发明名称 |
Biomarker for coronary artery disease |
摘要 |
In various embodiments methods are provided for identifying a mammal having an elevated risk for an adverse cardiac event (e.g. an MI) and/or determining the prognosis for the mammal. In certain embodiments the methods comprise determining, or causing to be determined, the presence and/or level of antibodies that bind a malondialdehyde-acetaldheyde adduct (MAA adduct) in a biological sample from the mammal, where an elevated level of anti-MAA adduct antibodies, as compared to the level found in a normal healthy mammal is an indicator that that said mammal has one or more atherosclerotic lesions and/or is at elevated risk for a myocardial infarction. |
申请公布号 |
AU2012229156(A1) |
申请公布日期 |
2013.10.31 |
申请号 |
AU20120229156 |
申请日期 |
2012.03.12 |
申请人 |
BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA |
发明人 |
THIELE, GEOFFREY M.;ANDERSON, DANIEL R.;DURYEE, MICHAEL J. |
分类号 |
G01N33/564;G01N33/68;G01N33/92 |
主分类号 |
G01N33/564 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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