发明名称 |
Compositions containing purine nucleosides and manganese and their uses |
摘要 |
This invention encompasses methods of preserving protein function by contacting a protein with a composition comprising one or more purine nucleosides (such as e.g., adenosine or uridine) and an antioxidant (such as e.g., manganese). In addition, the invention encompasses methods of treating and/or preventing a side effect of radiation exposure and methods of preventing a side effect of radiotherapy comprising administration of a pharmaceutically effective amount of a composition comprising one or more purine nucleosides (such as e.g., adenosine or uridine) and an antioxidant (such as e.g., manganese) to a subject in need thereof. The compositions may comprise D. radiodurans extracts. |
申请公布号 |
AU2008307308(B2) |
申请公布日期 |
2013.10.31 |
申请号 |
AU20080307308 |
申请日期 |
2008.08.18 |
申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY;THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. |
发明人 |
MATROSOVA, VERA K.;DALY, MICHAEL J.;WEHR, NANCY B.;LEVINE, RODNEY L.;GAIDAMAKOVA, ELENA K. |
分类号 |
A61K31/7076;A61K33/32;A61P39/00 |
主分类号 |
A61K31/7076 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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