发明名称 |
NOVEL BETA-ALANINE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT |
摘要 |
The present invention relates to novel beta-alanine derivatives, to the pharmaceutically acceptable salts thereof, and to a pharmaceutical composition comprising same as an active ingredient. The novel beta-alanine derivatives and pharmaceutically acceptable salts thereof according to the present invention may effectively inhibit the activity of DGAT1, which is an enzyme serving as a catalyst in the final step of the synthesis of neutral lipids, and therefore can be effectively used as a pharmaceutical composition for preventing or treating various diseases relating to lipid metabolism belonging to the group consisting of obesity, dyslipidemia, fatty liver, insulin resistance syndrome, and hepatitis. |
申请公布号 |
WO2013162298(A1) |
申请公布日期 |
2013.10.31 |
申请号 |
WO2013KR03557 |
申请日期 |
2013.04.25 |
申请人 |
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY;HANDOK PHARMACEUTICALS CO., LTD. |
发明人 |
AHN, JIN HEE;KANG, SEUNG KYU;H. S. PAGIRE;RHEE, SANG DAL;KIM, KI YOUNG;JUNG, WON HOON;BAE, MYUNG-AE;SONG, JIN SOOK;CHAE, CHONG HAK;AHN, SUNG HOON;KIM, KWANG-ROK |
分类号 |
C07C233/25;A61K31/16;A61P1/16;A61P3/04 |
主分类号 |
C07C233/25 |
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