发明名称 NOVEL BETA-ALANINE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT
摘要 The present invention relates to novel beta-alanine derivatives, to the pharmaceutically acceptable salts thereof, and to a pharmaceutical composition comprising same as an active ingredient. The novel beta-alanine derivatives and pharmaceutically acceptable salts thereof according to the present invention may effectively inhibit the activity of DGAT1, which is an enzyme serving as a catalyst in the final step of the synthesis of neutral lipids, and therefore can be effectively used as a pharmaceutical composition for preventing or treating various diseases relating to lipid metabolism belonging to the group consisting of obesity, dyslipidemia, fatty liver, insulin resistance syndrome, and hepatitis.
申请公布号 WO2013162298(A1) 申请公布日期 2013.10.31
申请号 WO2013KR03557 申请日期 2013.04.25
申请人 KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY;HANDOK PHARMACEUTICALS CO., LTD. 发明人 AHN, JIN HEE;KANG, SEUNG KYU;H. S. PAGIRE;RHEE, SANG DAL;KIM, KI YOUNG;JUNG, WON HOON;BAE, MYUNG-AE;SONG, JIN SOOK;CHAE, CHONG HAK;AHN, SUNG HOON;KIM, KWANG-ROK
分类号 C07C233/25;A61K31/16;A61P1/16;A61P3/04 主分类号 C07C233/25
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