| 摘要 |
<p>AbstractHAIR GROWTH PROMOTING AGENT CONTAINING15,15-DIFLUOROPROSTAGLANDIN F2, DERIVATIVE AS ACTIVE INGREDIENTThe present invention provides a new pharmaceutical application of a 15,15-difluoroprostaglandin F2a derivative. As a result of intensive studies in order to find a new phaLanaceutical application of a 15,1,5-dif1uoroprostaglandin2 derivat Ve, it was found that, in a European Phase III clinical trial for tafluprost, one of the l545-difluoroprdstaglandin F2a derivatives, with patients with open-angle glaucoma or ocular hypertenbion, tafluprost has actions,of groWing eyelashes, making eyelashes thicker, and changing the color thereof, that is, has an effect of promoting the growth of hair (eyelashes). Therefore, a. 15 , 15-difluoroprostaglandin F2a derivative is useful as a hair growth promoting agent, and is expected to be useful as an :active ingredient Of a preventive or: therapeutic agent for a disease associated with hair such as alopecia and ahair care product or a hair cosmetic product for regrowing hair, growing hair, increasing hair density, nourishing hair, or the like.</p> |
