发明名称 |
A METHOD OF DIFFERENTIATING ONCOGENIC CHANGES OF THE THYROID, A KIT TO EMBODY THE METHOD AND THE USE OF METALLOTHIONEIN (MT) FOR DIFFERENTIATING ONCOGENIC CHANGES OF THE THYROID |
摘要 |
A method of differentiating oncogenic changes of the thyroid encompassing follicular adenoma and follicular cancer, characterised in that in a sample of oncogenic tissue from a patient the expression of the metallothionein (MT) potein is evaluated using immunochistochemical methods using monoclonal anti-MT antibodies, the degree of intensity of the expression of metallothionein is evaluated under a light microscope using the semiquantitative IRS method according to Remmele, wherein if the degree of intensity of the expression of metallothionein is equal to or greater than 8 on the semiquantitative IRS scale then the presence of follicular cancer is indicated. |
申请公布号 |
EP2656078(A1) |
申请公布日期 |
2013.10.30 |
申请号 |
EP20110819026 |
申请日期 |
2011.12.21 |
申请人 |
WROCLAWSKIE CENTRUM BADAN EIT + SP. Z O.O. |
发明人 |
DZIEGIEL, PIOTR;PODHORSKA-OKOLOW, MARZENA;KROLICKA, ANNA;KOBIERZYCKI, CHRISTOPHER;PULA, BARTOSZ;PIOTROWSKA, ALEKSANDRA |
分类号 |
G01N33/68;G01N33/574 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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地址 |
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