METHOD FOR PRODUCING GLYCOPEPTIDE HAVING SIALYL SUGAR CHAIN, SIALYL SUGAR CHAIN-ADDED AMINO ACID DERIVATIVE TO BE USED IN SAME, AND GLYCOPEPTIDE

摘要

][Technical Promblem]To provide a method for manufacturing that enables to obtain a targeted glycopeptide harboring a sialyl sugar chain in high yield without decomposing sialic acid at a non-reducing terminal of sugar chain when the glycopeptide is synthesized by a Boc solid phase synthesis method.[Solution to Problem]The present invention is characterized in that the Boc sialylglycosylated amino acid derivative used in Boc solid phase synthesis method is one where the carboxyl group of the sialic acid at the sugar chain non-reducing terminal is protected with a phenacyl group.