BONNET APPARATUS FOR USE WITH FLUID REGULATORS.

摘要

Bonnet apparatus for use with fluid regulators are described. An example bonnet (206) includes a body (302) having a cavity (304) to receive a loading assembly (220) of the fluid regulator (200). A support structure (324) is disposed in the cavity (304) and extends across the cavity (304) to increase an impact toughness or strength of the body (302). Bonnet apparatus for use with fluid regulators are described. An example bonnet (206) includes a body (302) having a cavity (304) to receive a loading assembly (220) of the fluid regulator (200). A support structure (324) is disposed in the cavity (304) and extends across the cavity (304) to increase an impact toughness or strength of the body (302). The invention relates to novel benzodiazepine derivatives with antiproliferative activity and more specifically to novel benzodiazepine compounds of formula (I)-(VII). The invention also provides conjugates of the benzodiazepine compounds linked to a cell-binding agent. The invention further provides compositions and methods useful for inhibiting abnormal cell growth or treating a proliferative disorder in a mammal using the compounds or conjugates of the invention.