发明名称 |
SUBSTITUTED PYRIDINES AS SODIUM CHANNEL BLOCKERS |
摘要 |
The invention relates to substituted pyridine compounds of Formula I: (I) and the pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein R1a, R1b, R2a, R2b, R2c, A1, A2, and X are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain. |
申请公布号 |
EP2655330(A1) |
申请公布日期 |
2013.10.30 |
申请号 |
EP20110813366 |
申请日期 |
2011.12.21 |
申请人 |
PURDUE PHARMA LP |
发明人 |
NI, CHIYOU;PARK, MINNIE;SHAO, BIN;TAFESSE, LAYKEA;YAO, JIANGCHAO;YOUNGMAN, MARK;ZHOU, XIAOMING |
分类号 |
C07D213/75;A61K31/44;A61K31/4439;A61P25/00;C07D401/02;C07D401/12;C07D401/14 |
主分类号 |
C07D213/75 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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