发明名称 |
NOVEL PROTEIN PURIFICATION METHODS |
摘要 |
<p>The invention provides methods of reducing fouling of ultrafiltration membranes in processes wherein virus particles are removed from aqueous solutions comprising virus particles and at least one protein by adding a surfactant or non-surfactant, non-ionic agent to the aqueous solution prior to filtration. The invention also provides methods to dissociate protein aggregates or to reduce the formation of protein aggregates by adding a surfactant or non- surfactant, non- ionic agent to the protein solution.</p> |
申请公布号 |
SG193564(A1) |
申请公布日期 |
2013.10.30 |
申请号 |
SG20130070909 |
申请日期 |
2012.03.23 |
申请人 |
GENENTECH, INC. |
发明人 |
BROWN, ARICK;JI, JUNYAN;LIU, JUN;WANG, YUCHANG, JOHN |
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