发明名称 |
EYE DROPS |
摘要 |
The purpose of the invention is to maximize the efficacy of, minimize the incidence of side effects from, and improve the storage stability of eye drops that contain: a peptide (SSSR),the amino acid sequence of which is represented by Ser-Ser-Ser-Arg, or a pharmacologically acceptable salt thereof; and a peptide (FGLM), the amino acid sequence of which is represented by Phe-Gly-Leu-Met-NH 2 , or a pharmacologically acceptable salt thereof. The concentration ratio between the SSSR or a pharmacologically acceptable salt thereof and the FGLM or a pharmacologically acceptable salt thereof is between 1/15 and 1/50. The concentration of the SSSR or a pharmacologically acceptable salt thereof is between 0.001% and 0.3 % (w/v) and the concentration of the FGLM or a pharmacologically acceptable salt thereof is between 0.015% and 1.5% (w/V). The pH of the eye drops is maintained between 2.5 and 6.5. |
申请公布号 |
EP2481416(A4) |
申请公布日期 |
2013.10.30 |
申请号 |
EP20100818829 |
申请日期 |
2010.09.24 |
申请人 |
SANTEN PHARMACEUTICAL CO., LTD |
发明人 |
NAKAMURA, TAKAHIRO;NAKADA, YUICHIRO;NAGANO, TAKASHI;NAKAMURA, MASATSUGU |
分类号 |
A61K38/27;A61K9/00;A61K9/08;A61K38/07;A61K47/02;A61K47/04;A61P27/02;C07K5/103;C07K5/107 |
主分类号 |
A61K38/27 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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