发明名称 |
Compounds and compositions as c-Kit kinase inhibitors |
摘要 |
The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit or c-kit and PDGFR (PDGFRalpha, PDGFRbeta) kinases.
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申请公布号 |
US8569283(B2) |
申请公布日期 |
2013.10.29 |
申请号 |
US201213598213 |
申请日期 |
2012.08.29 |
申请人 |
MOLTENI VALENTINA;PETRASSI HANK MICHAEL JAMES;LI XIAOLIN;LIU XIAODONG;LOREN JON;NABAKKA JULIET;NGUYEN BAO;YEH VINCE |
发明人 |
MOLTENI VALENTINA;PETRASSI HANK MICHAEL JAMES;LI XIAOLIN;LIU XIAODONG;LOREN JON;NABAKKA JULIET;NGUYEN BAO;YEH VINCE |
分类号 |
A61K31/437;A61K31/4545;A61K31/496;A61K31/5377;A61P1/00;A61P1/16;A61P3/00;A61P3/10;A61P7/00;A61P9/12;A61P11/00;A61P11/02;A61P11/06;A61P17/00;A61P29/00;A61P37/00;A61P37/08;C07D471/04;C07D491/048;C07D491/107 |
主分类号 |
A61K31/437 |
代理机构 |
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地址 |
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