发明名称 |
Substituted 3-(1H-benzo[d]imidazol-2-yl)-1H-indazole analogs as inhibitors of the PDK1 kinase |
摘要 |
In one aspect, the invention relates to substituted 3-(1H-benzo[d]imidazol-2-yl)-1H-indazole analogs, derivatives thereof, and related compounds, which are useful as inhibitors of the PDK1 kinase; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions for treating disorders associated with dysfunction of the PDK1 kinase. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
申请公布号 |
US8569511(B2) |
申请公布日期 |
2013.10.29 |
申请号 |
US201213436905 |
申请日期 |
2012.03.31 |
申请人 |
BEARSS DAVID J.;VANKAYALAPATI HARIPRASAD;SORNA VENKATASWAMY;WARNER STEVEN L.;SHARMA SUNIL;UNIVERSITY OF UTAH RESEARCH FOUNDATION |
发明人 |
BEARSS DAVID J.;VANKAYALAPATI HARIPRASAD;SORNA VENKATASWAMY;WARNER STEVEN L.;SHARMA SUNIL |
分类号 |
A61K31/5377;A61K31/4184;A61K31/454;C07D401/14;C07D403/04;C07D413/14 |
主分类号 |
A61K31/5377 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|