发明名称 |
Substituted heteroarylamine carboxamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same |
摘要 |
Disclosed are negative allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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申请公布号 |
US8569308(B2) |
申请公布日期 |
2013.10.29 |
申请号 |
US20100885245 |
申请日期 |
2010.09.17 |
申请人 |
CONN P. JEFFREY;LINDSLEY CRAIG W.;EMMITTE KYLE A.;WEAVER CHARLES DAVID;RODRIGUEZ ALICE L.;FELTS ANDREW S.;JONES CARRIE K.;BATES BRITTNEY S.;VANDERBILT UNIVERSITY |
发明人 |
CONN P. JEFFREY;LINDSLEY CRAIG W.;EMMITTE KYLE A.;WEAVER CHARLES DAVID;RODRIGUEZ ALICE L.;FELTS ANDREW S.;JONES CARRIE K.;BATES BRITTNEY S. |
分类号 |
A01N37/30;A61K31/205 |
主分类号 |
A01N37/30 |
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地址 |
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