发明名称 |
1-benzyl-3-hydroxymethylindazole derivatives and use thereof in the treatment of diseases based on the expression of MCP-1 and CX3CR1 |
摘要 |
The present invention relates to novel 1-benzyl-3-hydroxymethylindazole derivatives according to formula (I) described in the claims, and to a pharmaceutical composition comprising them, together with a pharmaceutically acceptable vehicle. In addition, the present invention relates to the use of novel 1-benzyl-3-hydroxymethylindazole derivatives for the preparation of a pharmaceutical composition that is active in the treatment of diseases based on the expression of MCP-1 and CX3CR1, and to their use in a method for treating or preventing diseases based on the expression of MCP-1 and CX3CR1.
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申请公布号 |
US8569297(B2) |
申请公布日期 |
2013.10.29 |
申请号 |
US201213618948 |
申请日期 |
2012.09.14 |
申请人 |
GUGLIELMOTTI ANGELO;FURLOTTI GUIDO;MANGANO GIORGINA;CAZZOLLA NICOLA;AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. |
发明人 |
GUGLIELMOTTI ANGELO;FURLOTTI GUIDO;MANGANO GIORGINA;CAZZOLLA NICOLA |
分类号 |
A61K31/5377;A61K31/416;A61K31/4439;C07D231/56;C07D401/02;C07D413/02 |
主分类号 |
A61K31/5377 |
代理机构 |
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地址 |
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