发明名称 |
METHODS OF CREATING MODIFIED PROMOTERS RESULTING IN VARYING LEVELS OF GENE EXPRESSION |
摘要 |
The present invention relates to a method of creating promoter cassettes that include modified precursor promoters and transforming a population of bacterial host cells with a promoter library comprising the promoter cassettes resulting in bacterial clones having a range of expression levels of a gene of interest. The invention further relates to selecting a transformed bacterial host cell which has an optimum level of gene expression.
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申请公布号 |
CA2483006(C) |
申请公布日期 |
2013.10.29 |
申请号 |
CA20032483006 |
申请日期 |
2003.04.18 |
申请人 |
GENENCOR INTERNATIONAL, INC. |
发明人 |
CERVIN, MARGUERITE A.;VALLE, FERNANDO |
分类号 |
C12N15/70;C12N1/21;C12N15/10;C12N15/113;C12N15/63;C12N15/74;C12N15/75;C12N15/90;C40B40/02;C40B40/06;C40B50/06 |
主分类号 |
C12N15/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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