| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: group of inventions refers to whitening tooth pastes, adducts therefor, and methods for preparing them. The adduct applicable for preparing a whitening formulation is prepared by mixing raw materials comprising peroxide, urea and an alkali metal polyphosphate in aqueous solution in the environment of temperature and/or pressure and/or agitation effective to prepare a solution of raw materials. The relation of (alkali metal polyphosphate) to (peroxide) in the aqueous solution of the adduct is matched with the relation of (anhydrous alkali metal polyphosphate) to (hydrogen peroxide 35 wt/wt % of the concentration) falling within the range of 0.05:1 to 0.5:1, and the adduct has pH in the aqueous solution that increases at least by 1.0 after ten introductions of the solution.EFFECT: preparing the dental whitening formulation wherein the adduct is found in the aqueous environment, comprises a drug preparation and/or the adduct has pH in the aqueous solution that increases by at least 1,0 after ten introductions of the solution (and hence, in situ in the mouth when in use) that provides the excellent whitening properties thought to be ensured by the release of additional active peroxide ions onto the teeth when in use.15 cl, 4 ex |
