| 发明名称 |
Certain kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof |
| 摘要 |
<p>Disclosed herein are the used of 2-,4-,6-substituted pyrimidine compounds of formula I, wherein the substituents are as defined within the specification, in the manufacture of a medicament for the treatment of Huntington's disease.</p> |
| 申请公布号 |
NZ601483(A) |
申请公布日期 |
2013.10.25 |
| 申请号 |
NZ20090601483 |
申请日期 |
2009.08.04 |
| 申请人 |
CHDI FOUNDATION, INC. |
发明人 |
WITYAK, JOHN;TOLEDO-SHERMAN, LETICIA, M;DOMINGUEZ, CELIA;COURTNEY, STEPHEN, MARTIN;YARNOLD, CHRISTOPHER, JOHN;DE AGUIAR PENA, PAULA, CRISTINA;SCHEEL, ANDREAS;WINKLER, DIRK |
| 分类号 |
A61K31/426;A61K31/4453;A61K31/505;A61K31/506;C07D213/79;C07D213/81;C07D239/28;C07D239/42;C07D239/69;C07D401/04;C07D401/06;C07D401/12;C07D403/06;C07D405/12;C07D413/12;C07D417/12;C07D471/04 |
主分类号 |
A61K31/426 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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