DIG-5 INSECTICIDAL CRY TOXINS

摘要

Patent No. 596660 Disclosed is an isolated polypeptide comprising a core toxin segment selected from the group consisting of (a) a polypeptide comprising the amino acid sequence of residues114 to 655 of SEQ ID NO:2: EAVVSKALSELEGLRNALEGYTSALEAWQNNRSDKLKQLLVYERFVSTENLFKFAMPSFRSVGFEGPLLTVYAQAANLHLFLLKNAELFGAEWGMQQYEIDLFYNEQKGYVEEYTDHCVKWYNEGLNKLKNASGVKGKVWENYNRFRREMTIMVLDLLPLFPIYDARTYPMETVTELTRQIFTDPIGLTGINETKYPDWYGAASSEFVLIENRAIPKPGLFQWLTKINVRARVVEPNDRFAIWTGHSVVTQYTKSTTENTFNYGTSSGSTLSHTFDLLSKDIYQTYSIAAANKSATWYQA VPLLRLYGINASNVLSEDAFSFSNDIPSSKCKSTYSSDQLPIELLDEPIYGDLEEYGHRLSYVSEIFKETGSGTIPVLGWTHVSVRPDNKLYPDKITQLPAVKSTPYPEVKGLNVEKGPGFTGGDLVKVTASGNTLVRLKVKTDSPGTQKYRIRLKYAATSNFYLGAYAGSSGNNGIPGISSVPKTMDIGEPLSYTSFAYIDLPSSYTFSQTEEILKFVVNVFDSGGAIYADRVEFIPVDAD; (b) a polypeptide comprising an amino acid sequence having at least 90% sequence identity to the amino acid sequence of residues 114 to 655 of SEQ ID NO:2; (c) a polypeptide comprising an amino acid sequence of residues 114 to 655 of SEQ ID NO:2 with up to 20 amino acid substitutions, deletions, or modifications that do not adversely affect expression or activity of the toxin encoded by SEQ ID NO:2; or an insecticidally active fragment thereof.