INDICATORS FOR DETECTING THE PRESENCE OF METABOLIC BYPRODUCTS FROM MICROORGANISMS

摘要

ABSTRACT - 594174 The disclosure relates to a wound dressing suitable for visibly detecting microorganism growth at a wound site based on a colourless to colourful transformation of the dressing, said dressing comprising: (a) A barrier membrane forming a top surface of said wound dressing, which comprises transparent polymeric film; (b) a layer suitable for contacting bodily fluids from a wound site susceptible to microorganism growth which layer forms a bottom surface of said wound dressing; and (c) pH indicators comprising a plurality of hexamethoxy red and/or heptamethoxy red, for indicating the presence of acidic growth by-products in said layer from contaminating microorganisms, and wherein said hexamethoxy red and/or heptamethoxy red pH indicators are colorless at neutral pH of 7 and in the absence of a threshold level of microorganism growth by-products to colourful in the presence of a threshold level of microorganism growth by-products; and wherein the wound dressing further comprises a permeable membrane adjacent to the bottom surface of said polymeric film, wherein said permeable membrane is a hydrophilic, hydronium ion penetrating transparent polymeric film.