发明名称 |
OPTIMIZING UNGUAL TREATMENT BY QUANTITATIVE AUTORADIOGRAPHY |
摘要 |
<p>A method for optimizing ungual treatment includes (a) providing a nail having at least two spaced apart holes formed from a surface thereof and extending into the nail, and (b) topically applying a radiolabeled pharmaceutical composition to the nail. At least a portion of the composition is received in the at least two holes. The method also includes (c) sectioning a portion of the nail proximate the at least two holes into a plurality of sections, (d)determining, for each of the plurality of sections, a concentration of radio activity in the section as a function of position with respect to the at least two holes, and (e) optimizing a spacing between the at least two holes based at least partially on the determinations in step (d). A method of ungual treatment using the optimized spacing is also described.</p> |
申请公布号 |
WO2013156225(A1) |
申请公布日期 |
2013.10.24 |
申请号 |
WO2013EP55451 |
申请日期 |
2013.03.15 |
申请人 |
GALDERMA RESEARCH & DEVELOPMENT |
发明人 |
OSMAN-PONCHET, HANAN;BOUCLIER, MARTINE |
分类号 |
A61K51/12;A61K31/137;A61K51/04;A61P31/10 |
主分类号 |
A61K51/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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