| 发明名称 |
SOLID FORMS OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXAMIDE |
| 摘要 |
The present invention relates to crystalline solvate forms of N-[2,4-bis(1,1- dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1) and methods for their preparation. The present invention further relates to pharmaceutical compositions comprising the crystalline solvate forms, as well as methods of treatment therewith. |
| 申请公布号 |
CA2869847(A1) |
申请公布日期 |
2013.10.24 |
| 申请号 |
CA20122869847 |
申请日期 |
2012.04.20 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
LUISI, BRIAN;AREKAR, SNEHA GHANSHYAM;COSTACHE, ADRIANA;DINEHART, KIRK RAYMOND;JOHNSTON, STEVEN C.;NEUBERT-LANGILLE, BOBBIANNA J. |
| 分类号 |
C07D215/56;A61K31/47;A61P25/00 |
主分类号 |
C07D215/56 |
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