发明名称 |
REAGENTS AND TESTS DESIGNED FOR SCREENING AND FOLLOW-UP OF TYPE 2 DIABETES MELLITUS |
摘要 |
PURPOSE: A reagent for diagnosis and follow-up study on type 2 diabetes and a test method including a measurement of IL-1 beta are provided to accurately diagnose type 2 diabetes with convenience and comfortableness. CONSTITUTION: A novel method for diagnosing type 2 diabetes comprises the steps of: inducing macrophage from monocytes collected from blood of a person who is suspected to have diabetes and culturing the macrophage; measuring the concentration of active IL-1 beta secreted from the cultured macrophage; and determining type 2 diabetes when the concentration of active IL-1 beta is over a predetermined level. A method for determining treatment effects on type 2 diabetes comprises the steps of: inducing macrophage from monocytes collected from a patient's blood with a type 2 diabetes during treatment and culturing the macrophage; measuring the concentration of active IL-1 beta secreted from the cultured macrophage; and determining that a treatment has an effect on the patient when the concentration of active IL-1 beta is less than a predetermined level. [Reference numerals] (A) Patient with type 2 diabete before meformin treatment; (B) Patient with type 2 diabete after meformin treatment; (H) Ordinary person |
申请公布号 |
KR20130116797(A) |
申请公布日期 |
2013.10.24 |
申请号 |
KR20130027015 |
申请日期 |
2013.03.14 |
申请人 |
THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC) |
发明人 |
JO, EUN KYEONG;LEE, HYE MI;KU, BON JEONG |
分类号 |
G01N33/53;C12N5/0786;C12Q1/02 |
主分类号 |
G01N33/53 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|