发明名称 COMPOUNDS AND METHODS FOR REGULATING INTEGRINS
摘要 A method of treating inflammation, by administering an effective amount of a beta2 integrin agonist to a patient, and reducing inflammation. A method of treating cancer, by administering an effective amount of a beta2 integrin agonist to a patient, and reducing tumor growth. A method of treating a patient exposed to radiation, by administering an effective amount of a beta2 integrin agonist to the patient after radiation exposure, and mitigating the effects of radiation exposure in the patient. A method of preventing effects of radiation, by administering an effective amount of a beta2 integrin agonist to the patient prior to radiation exposure, and preventing the effects of radiation exposure on the patient. A method of treating acquired bone marrow failure (BMF), by administering an effective amount of a beta2 integrin agonist to a patient. Methods of improving the health of damaged vasculature in a patient and activating beta2 integrins.
申请公布号 WO2013159082(A1) 申请公布日期 2013.10.24
申请号 WO2013US37548 申请日期 2013.04.22
申请人 ADHAERE PHARMACEUTICALS, INC.;GUPTA, VINEET 发明人 GUPTA, VINEET
分类号 A61P37/02 主分类号 A61P37/02
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