发明名称 |
Intermedios y procesos para preparar el ácido 4-(acetilamino)-3-[(4-clorofenil)tio]-2-metil-1H-indol-1-acético |
摘要 |
The invention relates to compounds of formula (X), and salts thereof, and their use as intermediates in improved manufacturing processes for the synthesis of pharmaceutical compound (I): X is ═O, ═N—OH or ═N—OC(O)Me; Y is hydrogen, PhS- or p-chlorophenylsulfanyl; Z is hydrogen or —CH2COOR1 wherein R1 is selected from hydrogen, optionally substituted hydrocarbyl and optionally substituted heterocyclyl.
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申请公布号 |
ES2426679(T3) |
申请公布日期 |
2013.10.24 |
申请号 |
ES20100752114T |
申请日期 |
2010.07.05 |
申请人 |
ASTRAZENECA AB |
发明人 |
AINGE, DEBRA;BUTTERS, MICHAEL;MERIFIELD, ERIC;RAMAKRISHNAN, RAVI;RAYAPATI, RAVI NAIDU;SHARMA, PARHALAD RAY;THOMSON, COLIN |
分类号 |
C07D209/08;C07C251/32;C07D209/30 |
主分类号 |
C07D209/08 |
代理机构 |
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