发明名称 Intermedios y procesos para preparar el ácido 4-(acetilamino)-3-[(4-clorofenil)tio]-2-metil-1H-indol-1-acético
摘要 The invention relates to compounds of formula (X), and salts thereof, and their use as intermediates in improved manufacturing processes for the synthesis of pharmaceutical compound (I): X is ═O, ═N—OH or ═N—OC(O)Me; Y is hydrogen, PhS- or p-chlorophenylsulfanyl; Z is hydrogen or —CH2COOR1 wherein R1 is selected from hydrogen, optionally substituted hydrocarbyl and optionally substituted heterocyclyl.
申请公布号 ES2426679(T3) 申请公布日期 2013.10.24
申请号 ES20100752114T 申请日期 2010.07.05
申请人 ASTRAZENECA AB 发明人 AINGE, DEBRA;BUTTERS, MICHAEL;MERIFIELD, ERIC;RAMAKRISHNAN, RAVI;RAYAPATI, RAVI NAIDU;SHARMA, PARHALAD RAY;THOMSON, COLIN
分类号 C07D209/08;C07C251/32;C07D209/30 主分类号 C07D209/08
代理机构 代理人
主权项
地址