发明名称 |
METHOD FOR INCREASING THE SECRETION OF RECOMBINANT PROTEINS |
摘要 |
<p>The invention relates to a method for producing a recombinant protein in cells with a cell wall, comprising the step of increasing the secretion of the recombinant protein through the cell wall by expression of the protein in the cells in a culture medium containing a combination of a surface-active polymer and monovalent metal ions and with an osmolarity at least 0.32 osmol/L, said invention further relating to culture media and nutrient mixtures for the method.</p> |
申请公布号 |
CA2870587(A1) |
申请公布日期 |
2013.10.24 |
申请号 |
CA20132870587 |
申请日期 |
2013.04.17 |
申请人 |
GREENOVATION BIOTECH GMBH |
发明人 |
JOST, WOLFGANG;KNAPPENBERGER, MATHIAS;CLAUSSNITZER, DOREEN;SCHAAF, ANDREAS |
分类号 |
C12N15/82;C12N5/00;C12P21/02 |
主分类号 |
C12N15/82 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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